AXP® II System

Overview

Raising the Standard on Cord Blood Processing

The AXP® II System has been designed to provide high-quality stem cell concentration from cord blood. So when you are processing cord blood samples, using the AXP® II System, you can be confident that you are isolating and saving the highest concentration of stem cell rich buffy coat while retaining their viability.

Automation at its Finest

Cord blood is transferred into the processing bag set which is placed in the AXP Device and then centrifuged. The AXP Device fits into most standard blood bank centrifuge buckets allowing up to six samples to be processed simultaneously. During centrifugation, component stratification and separation occurs. Red blood cells (RBC) are transferred to a separate sterile bag, the buffy coat which contains the mononuclear cell (MNC) rich layer is delivered to a separate sterile freezing bag while the plasma remains in the processing bag. The AXP II System does not require the addition of hetastarch for successful capturing of MNCs.

 Complete System Solution

  • AXP® II Device

  • AXP® II Docking Station

  • AXP® Processing Bag Set

  • XpressTRAK® Software

  • Accessories

 

Highest Yields. Viable Cells.

  • Precise delivery of final volume target1

  • Reliable collection of all fractions: buffy coat, RBC, and plasma

  • Viable CD34+ stem cell recovery of >97% is higher than other available systems2

  • Cord blood units (CBU) processed with AXP are richer in mononuclear cells (MNC) than units conventionally processed having similar total nucleated cells (TNC)1

  • Hematocrit is consistently <30% in final storage volume1

 Uncompromising Safety. Quality Results.

  • Utilizes a functionally closed processing set

  • Separate collection bags for capturing buffy coat, plasma, and red blood cells

  • Integrated sampling pillows for pre- and post-processing sterile sample collection

  • Transferring cord blood from collection bag can be done by:

    • Sterile weld

    • Spike port

  • In-line clot filter and multiple sampling ports

  • Integrated DMSO inlet filter and tubing

 Efficient Automation. Integrated Quality Control. 

  • XpressTRAK® software tracks and documents data specific to each cord blood unit processed

  • Captures sample processing data to assist with quality assurance and compliance with current good tissue practices (cGTP) and good manufacturing practices (cGMP)

  • Stores processing data in a searchable, sortable database

  • Customizable data fields and reports

Training Video

INDICATION

The AXP® II System is a cord blood processing system intended for laboratory use in combination with a specific and compatible single-use separation kit supplied by ThermoGenesis. The AXP II System allows the fast, automated, and reproducible separation of cord blood in a closed and sterile environment.

1. Data on file.

2. Rubenstein P. Cord blood banking for clinical transplantation. Bone Marrow Transplantation 2009; 44:635-642.