CDMO: An Approach for Scalability and Manufacturing

Over the last few decades, cell therapies, such as stem cell and CAR-T, have become increasingly important in fighting cancer and are therefore creating a need for cell therapy companies to make these life-saving products available at a larger scale. Cell therapies have become personal, that is they can be tailor made to be an … Continued

Transient Warming Events and the Effects on Cell Viability

When it comes to cell processing and cell manufacturing, it’s extremely important that samples are collected and stored properly so that they retain the greatest viability for use in the future. As you can imagine, there are some logistical challenges associated with cryopreserving samples at just the right temperature for an extended period of time, … Continued

Red Blood Cells and the Effects of Cell Processing

What is Cell Processing Cell processing is the practice of concentrating, selecting and/or culturing cells from blood or blood products, for example bone marrow or cord blood, that can then be used to treat diseases.  The process begins with the collection of the blood or blood product (sample) from a person at a hospital or … Continued

Cell Storage Solutions for Cellular Manufacturing of Clinical Products

Cell and gene therapies have become increasingly popular in the last few decades, especially with the recent FDA approval of CAR T-cell therapies such as Kymriah and Yescarta. These life-changing therapies are the latest in scientific and technological advancements in the field of regenerative medicine and it is exciting to see the progress that has … Continued

Four Tips to Consider for Cryopreservation of Cell Therapies

Cryopreservation is the process of using ultra-low temperatures to preserve living cells for long periods of time. It is an essential aspect of the cell manufacturing process of many cell therapies. While there are multiple factors to consider for developing a cryopreservation process that will ensure safe and effective manufacturing of cell therapies, below are … Continued

The Importance of Automated Cell Washing for Cell Manufacturing

As more and more cell and gene therapies are being developed, there is an emerging need for the industrialization of cell manufacturing. With greater production also comes more regulation, and the industry is in need of processes that are scalable and still meet the requirements of Good Manufacturing Practices (GMP) for cell manufacturing.   Cell … Continued

35 Years of ThermoGenesis: A Timeline of Events

Throughout our 35-year history, ThermoGenesis Holdings, Inc. has undergone a variety of changes. However, through it all, we’ve never strayed from the heart of our mission which is to provide the world with quality automated cell processing technologies and solutions. 35 years ago, Halley’s Comet last visited the Milky Way, Oprah Winfrey debuted her national … Continued

Immunotherapies Used to Treat Cancer

Cancer is the second leading cause of death in the United States behind heart disease according to the CDC. There are many kinds, but what they all have in common is that they start because of out-of-control growth of abnormal cells. For decades, scientists and medical professionals have researched this disease, and while a cure … Continued

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