The Importance of Cryopreservation in GMP Cell Therapy Cryopreservation is a process that preserves cells and tissues by freezing samples to very low temperatures over a period of time. It’s important to the cell therapy manufacturing process because cell samples need to be properly stored in order to maintain their viability and functionality later down … Continued
Translating a drug from a concept to a treatment that is scalable and manufacturable can be the biggest challenge for developers of cell and gene therapies (CGT). Particularly in this field, the challenge is even greater because the people who are able to perform the necessary tasks need to be highly skilled cell biologists … Continued
Over the last few decades, cell therapies, such as stem cell and CAR-T, have become increasingly important in fighting cancer and are therefore creating a need for cell therapy companies to make these life-saving products available at a larger scale. Cell therapies have become personal, that is they can be tailor made to be an … Continued
When it comes to cell processing and cell manufacturing, it’s extremely important that samples are collected and stored properly so that they retain the greatest viability for use in the future. As you can imagine, there are some logistical challenges associated with cryopreserving samples at just the right temperature for an extended period of time, … Continued
What is Cell Processing Cell processing is the practice of concentrating, selecting and/or culturing cells from blood or blood products, for example bone marrow or cord blood, that can then be used to treat diseases. The process begins with the collection of the blood or blood product (sample) from a person at a hospital or … Continued
Overview of Cord Blood and its Uses Cord blood is blood found in the blood vessels of the placenta and the umbilical cord. It is collected after a baby is born and once the umbilical cord is cut, making it a safe procedure for both mother and baby. Cord blood is a good source of … Continued
Cell and gene therapies have become increasingly popular in the last few decades, especially with the recent FDA approval of CAR T-cell therapies such as Kymriah and Yescarta. These life-changing therapies are the latest in scientific and technological advancements in the field of regenerative medicine and it is exciting to see the progress that has … Continued
Cell and gene therapy are forms of medical treatment that have been at the forefront of research in the last few decades. A growing field of research, cell-based therapies involve modification of a patient’s own cells or cells from a donor to fight diseases or alleviate medical conditions to help patients continue to live their … Continued
Cryopreservation is the process of using ultra-low temperatures to preserve living cells for long periods of time. It is an essential aspect of the cell manufacturing process of many cell therapies. While there are multiple factors to consider for developing a cryopreservation process that will ensure safe and effective manufacturing of cell therapies, below are … Continued
As more and more cell and gene therapies are being developed, there is an emerging need for the industrialization of cell manufacturing. With greater production also comes more regulation, and the industry is in need of processes that are scalable and still meet the requirements of Good Manufacturing Practices (GMP) for cell manufacturing. Cell … Continued